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Rhodes University is a public research university located in Makhanda (Grahamstown) in the Eastern Cape Province of South Africa. It is one of four universities in the province. Established in 1904, Rhodes University is the province's oldest university, and it is the sixth oldest South African university in continuous operation, being preceded by the University of the Free State (1904), University of Witwatersrand (1896), University of South Africa (1873) as the University of the Cape of Good Hope, Stellenbosch University (1866) and the University of Cape Town (1829). Rhodes was founded in 1904 as Rhodes University College, named after Cecil Rhodes, through a grant from the Rhodes Trust. It became a constituent college of the University of South Africa in 1918 before becoming an independent university in 1951.

The university had an enrolment of over 8,000 students in the 2015 academic year, of whom just over 3,600 lived in 51 residences on campus, with the rest (known as Oppidans) taking residence in digs (off-campus residences) or in their own homes in the town.