| Center for International Students and Programs | Academic & Science |
| Computer Inventory of Survey Plans | Academic & Science |
| Center for Information Society and Policy | Academic & Science |
| California International Studies Project | Academic & Science |
| Commercial Internet Service Provider | Business |
| Certified IRA Service Professional | Business |
| Certified Inside Sales Professional | Business |
| Cambridge International Science Publishing | Business |
| Cooperative Income Sharing Program | Community |
| Community Investment Support Program | Community |
| Center for International Services and Programs | Community |
| Childhood Immunization Support Program | Community |
| Community Information Systems Project | Community |
| Congress on Image and Signal Processing | Community |
| Celtic Inscribed Stones Project | Community |
| Cellular Image Sensor Processor | Computing |
| Computer Info Science Program | Computing |
| Cardholder Information Security Program | Computing |
| Cyber Intelligence Sharing Platform | Computing |
| Certified IRA Services Professional | General |
| Construction Industry Service Program | General |
| Cast Iron Soil Pipe | General |
| Center for International Studies and Programs | General |
| Center for Invasive Species Prevention | General |
| Card Information Security Program | General |
| Community Interaction Subsidy Program | Governmental |
| Counter-Intelligence Support Plan | Governmental |
| Cyber Security Information Sharing Partnership | Governmental |
| Community Intensive Supervision Program | Governmental |
| Classification Internationale des Soins Primaires | International |
| Centro Italiano Smalti Porcellanati | International |
| Chronic Intractable Shoulder Pain | Medical |