| International Society for Aeolian Research | Academic & Science |
| International Society for Animal Rights International Society for | Academic & Science |
| Indian Society For Assisted Reproduction | Academic & Science |
| International Society of Arthroplasty Registries | Academic & Science |
| Indian Students At RICE | Academic & Science |
| International Symposium On Audit Research | Accounts and Finance |
| International Society for Astrological Research | Business |
| International Society for Antiviral Research | Business |
| Instant Specific Absorption Rate | Business |
| International Standards of Accounting and Reporting | Business |
| Infobase of State Activities and Research | Community |
| Indiana State Association of Remanufacturers | Community |
| Input Segmentation And Reassembly | Computing |
| Internet Security Assessment of Risks | Computing |
| Inteligible semi automated reasoning | General |
| Interpretive Services Appointment Record | General |
| Identification of Seniors At Risk | General |
| I Sure Am Rescue | General |
| Interactive Streaming for Augmented Reality | General |
| Information Saving And Retrieval | General |
| Industry Safety Accident Rating | General |
| Intracoronary Stenting and Antithrombotic Regimen | General |
| Intelligible Semi Automated Reasoning | General |
| International Space Analogue Rockstore | General |
| International Society for Animal Rights | General |
| Income Support Application Rejection | Governmental |
| Institute for the Study of Academic Racism | Governmental |
| International Symposium on Augmented Reality | International |
| International Symposium on Arctic Research | International |
| International Society for Auricular Reconstruction | International |
| International Search And Rescue | International |
| International Severe Asthma Registry | Medical |
| Inverse Synthetic Aperture Radar | Military and Defence |