| Service Parts Operations (General Motors) | Academic & Science |
| South Pole Observatory | Academic & Science |
| Student Peace Organization | Academic & Science |
| Student Post Office | Academic & Science |
| Student Professional Organization | Academic & Science |
| Student Production Office | Academic & Science |
| Student Performance Objectives | Academic & Science |
| Sponsored Projects Office | Academic & Science |
| Schizosaccharomyces Pombe | Academic & Science |
| Single Purpose Outlet | Academic & Science |
| Sales Promotion Office | Business |
| Sales Performance Optimization | Business |
| Skylon Global Capital Yield Trust II | Business |
| Senior Programme Officer | Business |
| Social Policy Obligations | Business |
| Sportech | Business |
| Seoul Philharmonic Orchestra | Community |
| Shanghai Philharmonic Orchestra | Community |
| Slovak Philharmonic Orchestra | Community |
| Sendai Philharmonic Orchestra | Community |
| Strengthening Participatory Organisation | Community |
| Sign Performance Outreach | Community |
| Sharepoint Online | Computing |
| Standard Pascal Object | Computing |
| Staffware Process Objects | Computing |
| Spores Network | Cryptocurrency |
| Strategic Plan Objectives | General |
| Small Project Observatory | General |
| Sacramento Peak Observatory | General |
| Space Pirate Organization | General |
| Service Process Optimization | General |
| Sick Psycho Obsessive | General |
| State Personnel Office | General |
| Sponsored Programs Office | General |
| Sustainability Performance Office | General |
| SharePoint Protocols Overview | General |
| Special Projects Office | General |
| Servicing Personnel Office | General |
| Self Prediction Optimality | General |
| Scientific Publications Office | General |
| Standardized Purchase Order | General |
| Sub Post Office | General |
| Saint Paul's Outreach | General |
| Sigma Phi Omega | General |
| Systems Program Office | General |
| State Property Office | General |
| Solmonese Parents Organization | General |
| Special Programs Office | General |
| Scientific Program Overview | General |
| Scale Polarize Offset | General |
| Supplier Purchase Order | General |
| Supply Path Optimisation | General |
| Smith Petersen osteotomy | General |
| Supply Path Optimization | General |
| SEO Product Optimizer | General |
| Service Point Oriflame | General |
| Shippensburg Produce and Outreach | General |
| Sponsored Project Office | General |
| Standing Purchase Order | General |
| Strategic Partnerships Office | General |
| Serving Post Office | General |
| Super Production Over | General |
| Sportabout | General |
| Single-Pilot Operation | General |
| Special Production Option | General |
| Service Parts Operation | General |
| Space Program Office | Governmental |
| Shore Patrol Officer | Governmental |
| Space Planning and Operations | Governmental |
| Strategic Planning Officer | Governmental |
| Senior Planning Officer | Governmental |
| Space Planning Operations | Governmental |
| Special Police Officer | Governmental |
| Senior Police Officer | Governmental |
| Supervisory Police Officer | Governmental |
| Student Police Officer | Governmental |
| Security Police Officer | Governmental |
| Srpski Pokret Obnove (Serbian: Serbian Renewal Movement; political party created in 1990) | Governmental |
| Senior Patrol Officer | Governmental |
| Special Palm Oil | Governmental |
| Service Provider Organization | Governmental |
| State Planning Office | Governmental |
| State Procurement Office | Governmental |
| Spokane, Washington | Governmental |
| Senate Press Office (Georgia) | Governmental |
| SURPURA | Indian Railway Station |
| Sektorowe Programy Operacyjne (Polish: Sectoral Operational Program) | International |
| Special Project Officer | Jobs |
| Smith-Peterson Osteotomy | Medical |
| Structure, Process and Outcome | Medical |
| Small Pack Option | Military and Defence |
| Security, Plans, and Operations | Military and Defence |
| Security and Plans Officer | Military and Defence |
| Special Project Office | Military and Defence |
| System Project Office | Military and Defence |
| Stoker Petty Officer | Regional |
| Statutory Publications Office | Regional |
| Slaithwaite Philharmonic Orchestra | Regional |
| Shuttle Projects Office | Space Science |
| Spare Parts Order | Space Science |
| System Program Office | Space Science |
| Secondary Public Offering | Stock Exchange |