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Call of Duty: Black Ops III is a 2015 first-person shooter video game, developed by Treyarch and published by Activision. It is the twelfth entry in the Call of Duty series and the sequel to the 2012 video game Call of Duty: Black Ops II. It was released on Microsoft Windows, PlayStation 4, and Xbox One on November 6, 2015. A feature-limited version developed by Beenox and Mercenary Technology that only supports multiplayer modes was released on PlayStation 3 and Xbox 360 and was also the final Call of Duty title released on those platforms.

Black Ops III takes place in 2065, 40 years after the events of Black Ops II, in a world facing upheaval from climate change and new technologies. Similar to its predecessors, the story follows a group of black ops soldiers. The game's campaign is designed to support 4-player cooperative gameplay, allowing for bigger, more open level design and less corridor shooting. As the player character is cybernetically enhanced, players have access to various special activities. The game also features a standalone Zombies campaign mode, and a "Nightmares" mode which replaces all enemies as zombies.

Announced on April 26, 2015, the game is the first Call of Duty video game released after Activision parted with Microsoft Studios and partnered with Sony Computer Entertainment, which secured the timed exclusivity of the game's downloadable content. Upon release, the game received generally positive reviews from critics, praising the gameplay, Zombies mode, and amount of content. However, it was also criticized for its story and lack of innovation. The seventh-generation console versions in particular were singled-out for their lack of a campaign and numerous features, as well as them being online-only. It was a commercial success, with it becoming the top-selling retail game in the US in 2015, and one of the most successful titles released for the eighth generation of video game consoles.

A sequel, Call of Duty: Black Ops 4, was released in October 2018.