OPTION 2. Deficiency of Thyroxine HORMONE causes Goitre.Goiter is a disease in which swelling occurs in the Thyroid gland present in your neck.Thyroxine is a hormone that is secreted into the bloodstream by the thyroid gland.This hormone plays a vital role in the PROPER functioning of Heart, Digestive system, metabolic activities etc.Iodine is the main component of Thyroxine hormone and deficiency of former leads to deficient production of the latter by the thyroid gland.Thyroid then works extra hard to produce the requisite Thyroxine hormone which leads to swelling in it and hence Goitre. HormoneFactsAdrenalineAlso known as Epinephrine.Produced by Adrenal glands and neurons in Medulla Oblongata.Increases Heartbeat, opens Bronchioles.Secreted in response to fear, panic or threat.ThyroxineAlso known as T4; Tetraiodothyronine.Released by the Thyroid gland.Plays a vital role in the proper functioning of Heart, Digestive system, metabolic activities, etc.EstrogenSex hormones of women.Produced by Ovaries and Adrenal Glands.It causes the growth of women's physical features during puberty.TestosteroneMainly produced in men by Testicles.Plays a vital role in the development of male reproductive organs and sperm production.