ISRU meaning in General ?

In space exploration, in situ resource utilization (ISRU) is the practice of collection, processing, storing and use of materials found or manufactured on other astronomical objects (the Moon, Mars, asteroids, etc.) that replace materials that would otherwise be brought from Earth.

ISRU could provide materials for life support, propellants, construction materials, and energy to a spacecraft payloads or space exploration crews. It is now very common for spacecraft and robotic planetary surface mission to harness the solar radiation found in situ in the form of solar panels. The use of ISRU for material production has not yet been implemented in a space mission, though several field tests in the late 2000s demonstrated various lunar ISRU techniques in a relevant environment.

ISRU has long been considered as a possible avenue for reducing the mass and cost of space exploration architectures, in that it may be a way to drastically reduce the amount of payload that must be launched from Earth in order to explore a given planetary body. According to NASA, "in-situ resource utilization will enable the affordable establishment of extraterrestrial exploration and operations by minimizing the materials carried from Earth."