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Wuxi (Chinese: 无锡) is a city in southern Jiangsu province, eastern China, 135 kilometers (84 mi) by car to the northwest of downtown Shanghai, between Changzhou and Suzhou. In 2017 it had a population of 3,542,319, with 6,553,000 living in the entire prefecture-level city area. By the end of 2019, the city's registered population was 5.0283 million.

Wuxi is a prominent historical and cultural city of China, and has been a thriving economic center since ancient times as a production as an export hub of rice, silk and textiles. In the last few decades it has emerged as a major producer of electrical motors, software, solar technology and bicycle parts. The city lies in the southern delta of the Yangtze River and on Lake Tai, which with its 48 islets is popular with tourists. Notable landmarks include Lihu Park, the Mt. Lingshan Grand Buddha Scenic Area and its 88-meter (289 ft)-tall Grand Buddha at Ling Shan statue, Xihui Park, Wuxi Zoo and Taihu Lake Amusement Park and the Wuxi Museum.

The city is served by Sunan Shuofang International Airport, which opened in 2004, the Wuxi Metro, opened in 2014, and the Shanghai–Nanjing Intercity High-Speed Railway which connects it to Shanghai.

Wuxi is also a major city among the top 500 cities in the world by scientific research outputs, as tracked by the Nature Index and home to Jiangnan University, the only key national university of “Project 211” in the city.