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The Grand Prix of Cleveland was an Indy car event in the CART series, held annually at Burke Lakefront Airport in Cleveland, Ohio. The race celebrated its milestone 25th anniversary in 2006. The race was most recently held in 2007. After the 2008 open wheel unification, the 2008 race had to be cancelled. Attempts to revive the race have not yet come to fruition.

Normally a fully functioning airport year-round, Burke Lakefront Airport was shut down for the week leading up to the event each year, requiring careful maintenance of the runways in order to keep them safe for cars at high speeds. The race was very popular amongst fans, as the long, wide, runways (much wider and longer than typical courses) allowed for side-by-side racing, fast speeds, and superb passing zones around the entire track. The layout and overall flatness of the circuit also allowed a view of nearly the entire course from the grandstands. The track was less popular with drivers, as the runways were much bumpier than normal asphalt courses. The first turn, in which the runway narrowed and the cars turned at an almost 45 degree angle at the end of the front straight, was seen as one of the toughest in the circuit.